Understanding Sciatica
Sciatica is a term used to describe the symptoms of leg pain, tingling, numbness, or weakness that travel down the low back via the sciatic nerve in the back of the leg. Sciatica (sometimes known as radiculopathy) is a description of symptoms, not a diagnosis. A herniated disc, spinal stenosis, degenerative disc disease, and spondylolisthesis can all cause sciatica.
The mechanism of sciatic nerve injury is either a result of direct nerve compression, inflammation, an abnormal immune system response of the body, or a combination of all these factors.
Sciatica Causes and Symptoms Video
Common causes of sciatica include:
- Lumbar herniated disc. Research suggests that up to 90% of sciatica is caused by a lumbar herniated disc. The herniated disc typically compresses one or more spinal nerve roots (L4-S3) that form the sciatic nerve. A lumbar herniated disc can cause sciatica in two ways:
- Direct compression. Direct compression of the sciatic nerve can occur when a lumbar disc bulges (contained-disc-disorder) or when the soft inner material of the disc leaks out or herniates through the fibrous outer core (non-contained disc disorder) and presses against the nerve.
- Chemical inflammation. An acidic chemical irritant from the disc material (hyaluronan) may leak out and cause inflammation and irritation in the area around the sciatic nerve.
- Herniated Disc. A herniated disc may compress the sciatic nerve on one side, causing symptoms in one leg, or the disc may bulge or herniate from both sides, causing symptoms in both legs (bilateral sciatica). Bilateral sciatica may also be caused by two adjacent segments discs herniating on either side, although this possibility is rare.
- Degeneration. Degeneration of tissues in the lumbar spine can compress or irritate the sciatic nerve. Degeneration of the facet joints can also cause the synovial tissue in the joint's capsule to inflame and increase in bulk. Degeneration of vertebral bone may cause abnormal bone growths (bone spurs or osteophytes). These abnormally bulky tissues in the lumbar spine may cause compression of one or more nerve roots of the sciatic nerve. Degenerated intervertebral discs may secrete inflammatory proteins, causing inflammation of the sciatic nerve.
- Lumbar spinal stenosis. Spinal stenosis is the narrowing of the spinal canal and is relatively common in adults older than age 60. Research suggests that lateral recess stenosis may be common in causing sciatica in the elderly population.
- Spondylolisthesis. Spondylolisthesis occurs when a small stress fracture causes one vertebral body to slip forward on another. For example, the L5 vertebra may slip forward over the S1 vertebra. Sciatica may result from nerve compression following the disc space collapse, fracture, and forward slipping of the vertebral body. Spondylolisthesis may cause bilateral sciatica and is more common in younger adults.
These conditions may develop over time or spontaneously due to trauma or physical stress injury. Motor vehicle accidents, sports injuries, or falls may cause direct injury to the sciatic nerve. Conditions such as spondylolisthesis and herniated discs may develop from physical stress injuries, such as from weightlifting.
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